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Epigenetic therapy in allogeneic hematopoietic stem cell transplantation

DNA methylation and other epigenetic phenomena appear to be relevant in the pathogenesis of several malignant disorders. DNA methyltransferases add methyl groups to cytosine-phosphate-guanine (CpG) islandsleading to gene promoter silencing. The DNA methyltransferases inhibitors azacitidine and decit...

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Bibliografski detalji
Glavni autori: Bashir, Qaiser, William, Basem Magdy, Garcia-Manero, Guillermo, de Lima, Marcos
Format: Artigo
Jezik:Inglês
Izdano: Associação Brasileira de Hematologia e Hemoterapia 2013
Teme:
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3672123/
https://ncbi.nlm.nih.gov/pubmed/23741191
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.5581/1516-8484.20130034
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