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Epigenetic therapy in allogeneic hematopoietic stem cell transplantation

DNA methylation and other epigenetic phenomena appear to be relevant in the pathogenesis of several malignant disorders. DNA methyltransferases add methyl groups to cytosine-phosphate-guanine (CpG) islandsleading to gene promoter silencing. The DNA methyltransferases inhibitors azacitidine and decit...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Bashir, Qaiser, William, Basem Magdy, Garcia-Manero, Guillermo, de Lima, Marcos
Format: Artigo
Sprache:Inglês
Veröffentlicht: Associação Brasileira de Hematologia e Hemoterapia 2013
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3672123/
https://ncbi.nlm.nih.gov/pubmed/23741191
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.5581/1516-8484.20130034
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