Topoisomerase inhibitors can selectively interfere with different stages of simian virus 40 DNA replication.

I have found that antineoplastic drugs which are known to be inhibitors of mammalian DNA topoisomerases have pronounced and selective effects on simian virus 40 DNA replication. Ellipticine, 4'-(9-acridinylamino)methanesulfon-m-aniside, and Adriamycin blocked decatenation of newly replicated si...

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Bibliographic Details
Main Author: Snapka, R M
Format: Artigo
Language:Inglês
Published: 1986
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Research Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC367202/
https://ncbi.nlm.nih.gov/pubmed/3025645
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