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Celastrol induces apoptosis of gastric cancer cells by miR-146a inhibition of NF-κB activity

BACKGROUND: Celastrol, a plant triterpene, is known to play important role in inhibiting proliferation and inducing apoptosis of gastric cancer cells. In the present study, the mechanism of celastrol on gastric cancer cells apoptosis was examined. METHODS: We assessed effect of celastrol on NF-κB si...

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Detalhes bibliográficos
Main Authors: Sha, Min, Ye, Jun, Zhang, Li-xin, Luan, Zheng-yun, Chen, Ya-bao
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3672015/
https://ncbi.nlm.nih.gov/pubmed/23706078
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1475-2867-13-50
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