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Blocking Mineralocorticoid Receptors Impairs, Blocking Glucocorticoid Receptors Enhances Memory Retrieval in Humans

Memory retrieval is impaired at very low as well as very high cortisol levels, but not at intermediate levels. This inverted-U-shaped relationship between cortisol levels and memory retrieval may originate from different roles of the mineralocorticoid (MR) and glucocorticoid receptor (GR) that bind...

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Detalhes bibliográficos
Main Authors: Rimmele, Ulrike, Besedovsky, Luciana, Lange, Tanja, Born, Jan
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3671995/
https://ncbi.nlm.nih.gov/pubmed/23303058
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/npp.2012.254
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