Extensive mutagenesis of the nuclear location signal of simian virus 40 large-T antigen.

Site-directed mutagenesis was used to change Lys-128 of the simian virus 40 large-T nuclear location signal to Met, Ile, Arg, Gln, Asn, Leu, or His. Except for the large-T antigen of the Arg mutation, which was present in cytoplasmic and nuclear compartments, the resultant proteins were unable to en...

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Hlavní autoři: Colledge, W H, Richardson, W D, Edge, M D, Smith, A E
Médium: Artigo
Jazyk:Inglês
Vydáno: 1986
Témata:
Research Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC367186/
https://ncbi.nlm.nih.gov/pubmed/3025638
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