The different radiosensitivity when combining erlotinib with radiation at different administration schedules might be related to activity variations in c-MET-PI3K-AKT signal transduction

OBJECTIVES: The aim of this paper was to investigate the efficacy and activity variation associated with phosphoinositide 3-kinase (PI3K) signal transduction when combining erlotinib with radiation, using different administration schedules. MATERIALS AND METHODS: Erlotinib was delivered to A973 canc...

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Bibliografiske detaljer
Main Authors: Zhuang, Hong-Qing, Bo, Qi-Fu, Yuan, Zhi-Yong, Wang, Jun, Zhao, Lu-Jun, Wang, Ping
Format: Artigo
Sprog:Inglês
Udgivet: Dove Medical Press 2013
Fag:
Original Research
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3671795/
https://ncbi.nlm.nih.gov/pubmed/23745052
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2147/OTT.S44505
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