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Development and characterization of a specific IgG monoclonal antibody toward the Lewis x antigen using splenocytes of Schistosoma mansoni-infected mice

The parasitic blood fluke Schistosoma mansoni synthesizes immunogenic glycans containing the human Lewis x antigen (Le(x); Galactose-β1-4(Fucα1-3)N-acetylglucosamine-β-R, also called CD15), but the biological role(s) of this antigen in the parasites and in humans is poorly understood. To develop IgG...

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Detalhes bibliográficos
Main Authors: Mandalasi, Msano, Dorabawila, Nelum, Smith, David F, Heimburg-Molinaro, Jamie, Cummings, Richard D, Nyame, A Kwame
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3671776/
https://ncbi.nlm.nih.gov/pubmed/23542315
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/glycob/cwt025
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