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Purification from a human hepatoma cell line of a basic fibroblast growth factor-like molecule that stimulates capillary endothelial cell plasminogen activator production, DNA synthesis, and migration.

A 17,500-dalton protein which stimulates plasminogen activator production in cultured bovine capillary endothelial cells has been purified from a SK-Hep-1 human hepatoma cell lysate by using heparin affinity chromatography and fast protein-liquid ion exchange chromatography. The purified molecule st...

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Publicat a:Mol Cell Biol
Autors principals: Presta, M, Moscatelli, D, Joseph-Silverstein, J, Rifkin, D B
Format: Artigo
Idioma:Inglês
Publicat: Taylor & Francis 1986
Matèries:
Accés en línia:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC367172/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/3025628/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/mcb.6.11.4060-4066.1986
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