Synergistic Effect of Lupenone and Caryophyllene Oxide against Trypanosoma cruzi

The in vitro trypanocidal activity of a 1 : 4 mixture of lupenone and caryophyllene oxide confirmed a synergistic effect of the terpenoids against epimastigotes forms of T. cruzi (IC(50) = 10.4 μg/mL, FIC = 0.46). In addition, testing of the terpenoid mixture for its capacity to reduce the number of...

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Detalhes bibliográficos
Main Authors: Polanco-Hernández, Glendy, Escalante-Erosa, Fabiola, García-Sosa, Karlina, Rosado, María E., Guzmán-Marín, Eugenia, Acosta-Viana, Karla Y., Giménez-Turba, Alberto, Salamanca, Efraín, Peña-Rodríguez, Luis M.
Formato: Artigo
Idioma:Inglês
Publicado em: Hindawi Publishing Corporation 2013
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3671683/
https://ncbi.nlm.nih.gov/pubmed/23762135
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/2013/435398
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