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A critical evaluation of random copolymer mimesis of homogeneous antimicrobial peptides

Polymeric synthetic mimics of antimicrobial peptides (SMAMPs) have recently demonstrated similar antimicrobial activity as natural antimicrobial peptides (AMPs) from innate immunity. This is surprising, since polymeric SMAMPs are heterogeneous in terms of chemical structure (random sequence) and con...

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Bibliographic Details
Main Authors: Hu, Kan, Schmidt, Nathan W., Zhu, Rui, Jiang, Yunjiang, Lai, Ghee Hwee, Wei, Gang, Palermo, Edmund F., Kuroda, Kenichi, Wong, Gerard C. L., Yang, Lihua
Format: Artigo
Language:Inglês
Published: 2013
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3671498/
https://ncbi.nlm.nih.gov/pubmed/23750051
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/ma302577e
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