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Regulation of adenovirus gene expression in human WI38 cells by an E1B-encoded tumor antigen.

Adenovirus mutants carrying alterations in the gene encoding the E1B 19-kilodalton tumor antigen (19K protein) cause enhanced cytopathic effect (cyt phenotype) and the degradation of host-cell chromosomal DNA (deg phenotype) upon infection of human HeLa or KB cells. Furthermore, E1B 19K gene mutant...

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Detalles Bibliográficos
Main Authors: White, E, Faha, B, Stillman, B
Formato: Artigo
Idioma:Inglês
Publicado: 1986
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC367137/
https://ncbi.nlm.nih.gov/pubmed/2948107
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