The chromodomain helicase Chd4 is required for Polycomb-mediated inhibition of astroglial differentiation

Polycomb group (PcG) proteins form transcriptional repressor complexes with well-established functions during cell-fate determination. Yet, the mechanisms underlying their regulation remain poorly understood. Here, we extend the role of Polycomb complexes in the temporal control of neural progenitor...

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Hauptverfasser: Sparmann, Anke, Xie, Yunli, Verhoeven, Els, Vermeulen, Michiel, Lancini, Cesare, Gargiulo, Gaetano, Hulsman, Danielle, Mann, Matthias, Knoblich, Juergen A, van Lohuizen, Maarten
Format: Artigo
Sprache:Inglês
Veröffentlicht: European Molecular Biology Organization 2013
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Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3671258/
https://ncbi.nlm.nih.gov/pubmed/23624931
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/emboj.2013.93
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