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Bidirectional promoter elements of simian virus 40 are required for efficient replication of the viral DNA.

Mutants of simian virus 40 (SV40) lacking parts of the 72- and 21-base-pair repeat regions were made deficient in large T antigen by recombination with dlA 4000, a mutant containing a frameshift deletion near the amino terminus of the T antigen genes. These double mutants were transfected into COS c...

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Autores principales: Hertz, G Z, Mertz, J E
Formato: Artigo
Lenguaje:Inglês
Publicado: 1986
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC367100/
https://ncbi.nlm.nih.gov/pubmed/3025597
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