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CHRONIC PULMONARY LPS TOLERANCE INDUCES SELECTIVE IMMUNOSUPPRESSION WHILE MAINTAINING THE NEUTROPHILIC RESPONSE

LPS challenge causes potent activation of innate immunity. Because LPS is ubiquitously present in ambient air, repeated inhalation may lead to activation of the pulmonary immune response. If this activation is unregulated, chronic LPS inhalation would lead to persistent inflammation and organ damage...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Natarajan, Sudha, Kim, Jiyoun, Remick, Daniel G.
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2010
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3670960/
https://ncbi.nlm.nih.gov/pubmed/19487981
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1097/SHK.0b013e3181aa9690
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