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Identification of separate domains in the adenovirus E1A gene for immortalization activity and the activation of virus early genes.

The transformation and early adenovirus gene transactivation functions of the E1A region were analyzed with deletion and point mutations. Deletion of amino acids from position 86 through 120 had little effect on the lytic or transforming functions of the E1A products, while deletion of amino acids f...

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Détails bibliographiques
Publié dans:Mol Cell Biol
Auteurs principaux: Moran, E, Zerler, B, Harrison, T M, Mathews, M B
Format: Artigo
Langue:Inglês
Publié: Taylor & Francis 1986
Sujets:
Accès en ligne:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC367095/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/3025595/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/mcb.6.10.3470-3480.1986
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