Assessing SNP-SNP Interactions among DNA Repair, Modification and Metabolism Related Pathway Genes in Breast Cancer Susceptibility

Genome-wide association studies (GWASs) have identified low-penetrance common variants (i.e., single nucleotide polymorphisms, SNPs) associated with breast cancer susceptibility. Although GWASs are primarily focused on single-locus effects, gene-gene interactions (i.e., epistasis) are also assumed t...

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Detalhes bibliográficos
Main Authors: Sapkota, Yadav, Mackey, John R., Lai, Raymond, Franco-Villalobos, Conrado, Lupichuk, Sasha, Robson, Paula J., Kopciuk, Karen, Cass, Carol E., Yasui, Yutaka, Damaraju, Sambasivarao
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2013
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3670937/
https://ncbi.nlm.nih.gov/pubmed/23755158
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0064896
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