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Pyrimidine dimers block simian virus 40 replication forks.

UV light produces lesions, predominantly pyrimidine dimers, which inhibit DNA replication in mammalian cells. The mechanism of inhibition is controversial: is synthesis of a daughter strand halted at a lesion while the replication fork moves on and reinitiates downstream, or is fork progression itse...

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Bibliografische gegevens
Gepubliceerd in:Mol Cell Biol
Hoofdauteurs: Berger, C A, Edenberg, H J
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: Taylor & Francis 1986
Onderwerpen:
Online toegang:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC367092/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/3025594/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/mcb.6.10.3443-3450.1986
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