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Polyamines Inhibit Porin-Mediated Fluoroquinolone Uptake in Mycobacteria

Polyamines decrease the permeability of the outer membrane of Escherichia coli to fluoroquinolones and β-lactams. In this study, we tested the effect of four polyamines (spermidine, spermine, cadaverine and putrescine) on fluoroquinolone uptake in Mycobacterium bovis BCG. Our results show that polya...

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Autores principales: Sarathy, Jansy Passiflora, Lee, Edmund, Dartois, Véronique
Formato: Artigo
Lenguaje:Inglês
Publicado: Public Library of Science 2013
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC3670895/
https://ncbi.nlm.nih.gov/pubmed/23755283
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0065806
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