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Treponema denticola Major Outer Sheath Protein Impairs the Cellular Phosphoinositide Balance That Regulates Neutrophil Chemotaxis

The major outer sheath protein (Msp) of Treponema denticola inhibits neutrophil polarization and directed chemotaxis together with actin dynamics in vitro in response to the chemoattractant N-formyl-methionine-leucine-phenylanine (fMLP). Msp disorients chemotaxis through inhibition of a Rac1-depende...

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Autori principali: Visser, Michelle B., Sun, Chun-Xiang, Koh, Adeline, Ellen, Richard P., Glogauer, Michael
Natura: Artigo
Lingua:Inglês
Pubblicazione: Public Library of Science 2013
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3670873/
https://ncbi.nlm.nih.gov/pubmed/23755300
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0066209
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