Platelet Activation Determines Angiopoietin-1 and VEGF Levels in Malaria: Implications for Their Use as Biomarkers

INTRODUCTION: The angiogenic proteins angiopoietin (Ang)-1, Ang-2 and vascular endothelial growth factor (VEGF) are regulators of endothelial inflammation and integrity. Since platelets store large amounts of Ang-1 and VEGF, measurement of circulation levels of these proteins is sensitive to platele...

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Main Authors: Brouwers, Judith, Noviyanti, Rintis, Fijnheer, Rob, de Groot, Philip G., Trianty, Leily, Mudaliana, Siti, Roest, Mark, Syafruddin, Din, van der Ven, Andre, de Mast, Quirijn
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2013
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3670845/
https://ncbi.nlm.nih.gov/pubmed/23755151
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0064850
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