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Malignant transformation of murine fibroblasts by a human c-Ha-ras-1 oncogene does not require a functional epidermal growth factor receptor.

Although mutations in ras genes are thought to be important for the development of about 20% of human tumors, almost nothing is known about the way in which these mutations lead to cellular transformation. The known biochemical properties of the 21-kilodalton ras proteins suggest that they may behav...

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Bibliografiska uppgifter
Huvudupphovsmän: McKay, I A, Malone, P, Marshall, C J, Hall, A
Materialtyp: Artigo
Språk:Inglês
Publicerad: 1986
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Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC367084/
https://ncbi.nlm.nih.gov/pubmed/3796584
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