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Atomic Force Microscopy Reveals Drebrin Induced Remodeling of F-Actin with Subnanometer Resolution

We show by high-resolution atomic force microscopy analysis that drebrin A (a major neuronal actin binding protein) induced F-actin structural and mechanical remodeling involves significant changes in helical twist and filament stiffness (+55% persistence length). These results provide evidence of a...

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Autors principals: Sharma, Shivani, Grintsevich, Elena E., Phillips, Martin L., Reisler, Emil, Gimzewski, James K.
Format: Artigo
Idioma:Inglês
Publicat: 2010
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3670797/
https://ncbi.nlm.nih.gov/pubmed/21175132
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/nl104159v
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