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trans-Complementation of HBV rtM204I mutant replication by HBV wild-type polymerase

The function of the hepatitis B virus (HBV) wild-type (WT) polymerase (pol) expressed alone or in the context of the intact genome when interacting with HBV rtM204I in HepG2 cells was compared. We show that WT pol expression from a packaging-defective RNA can complement defective rtM204I pol activit...

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書誌詳細
主要な著者: Heipertz, Richard A., Starkey, Jason L., Miller, Thomas G., Hu, Jianming, Isom, Harriet C.
フォーマット: Artigo
言語:Inglês
出版事項: 2009
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC3670753/
https://ncbi.nlm.nih.gov/pubmed/19383566
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.virol.2009.03.018
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