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Maximum Likelihood Estimation of Frequencies of Known Haplotypes from Pooled Sequence Data

DNA samples are often pooled, either by experimental design or because the sample itself is a mixture. For example, when population allele frequencies are of primary interest, individual samples may be pooled together to lower the cost of sequencing. Alternatively, the sample itself may be a mixture...

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Bibliografski detalji
Glavni autori: Kessner, Darren, Turner, Thomas L., Novembre, John
Format: Artigo
Jezik:Inglês
Izdano: Oxford University Press 2013
Teme:
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3670732/
https://ncbi.nlm.nih.gov/pubmed/23364324
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/molbev/mst016
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