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Hypoxia-induced collagen crosslinking as a mechanism for enhancing mechanical properties of engineered articular cartilage

OBJECTIVE: The focus of tissue engineering of neocartilage has traditionally been on enhancing extracellular matrix and thus biomechanical properties. Emphasis has been placed on the enhancement of collagen type and quantity, and, concomitantly, tensile properties. The objective of this study was to...

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Detalhes bibliográficos
Main Authors: Makris, E.A., Hu, J.C., Athanasiou, K.A.
Formato: Artigo
Idioma:Inglês
Publicado em: 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3670708/
https://ncbi.nlm.nih.gov/pubmed/23353112
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.joca.2013.01.007
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