Lataa...

Point mutation associated with hereditary persistence of fetal hemoglobin decreases RNA polymerase III transcription upstream of the affected gamma-globin gene.

A base substitution in the 5'-flanking region of a human fetal globin gene is associated with abnormal fetal hemoglobin production. It also reduces by 5- to 10-fold in vitro transcription of the gene by RNA polymerase III. We discuss potential links between polymerase III transcription and abno...

Täydet tiedot

Tallennettuna:
Bibliografiset tiedot
Päätekijät: Carlson, D P, Ross, J
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: 1986
Aiheet:
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC367066/
https://ncbi.nlm.nih.gov/pubmed/2431298
Tagit: Lisää tagi
Ei tageja, Lisää ensimmäinen tagi!