Assessment of DNA methylation status in early stages of breast cancer development

BACKGROUND: Molecular pathways determining the malignant potential of premalignant breast lesions remain unknown. In this study, alterations in DNA methylation levels were monitored during benign, premalignant and malignant stages of ductal breast cancer development. METHODS: To study epigenetic eve...

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Hlavní autoři: van Hoesel, A Q, Sato, Y, Elashoff, D A, Turner, R R, Giuliano, A E, Shamonki, J M, Kuppen, P J K, van de Velde, C J H, Hoon, D S B
Médium: Artigo
Jazyk:Inglês
Vydáno: Nature Publishing Group 2013
Témata:
Molecular Diagnostics
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3670495/
https://ncbi.nlm.nih.gov/pubmed/23652305
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/bjc.2013.136
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