Speculations on the activation of ROS generation in C. elegans innate immune signaling

We recently published work demonstrating that ROS (reactive oxygen species) generated by the dual oxidase, Ce-Duox1/BLI-3, in response to infection in Caenorhabditis elegans activates the transcription factor SKN-1, initiating a protective response. Moreover, we showed that the crucial innate immune...

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Bibliographic Details
Main Authors: van der Hoeven, Ransome, McCallum, Katie C., Garsin, Danielle A.
Format: Artigo
Language:Inglês
Published: Landes Bioscience 2012
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3670408/
https://ncbi.nlm.nih.gov/pubmed/24058842
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4161/worm.19767
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