Murine leukemia virus glycosylated Gag blocks apolipoprotein B editing complex 3 and cytosolic sensor access to the reverse transcription complex

Pathogenic retroviruses have evolved multiple means for evading host restriction factors such as apolipoprotein B editing complex (APOBEC3) proteins. Here, we show that murine leukemia virus (MLV) has a unique means of counteracting APOBEC3 and other cytosolic sensors of viral nucleic acid. Using vi...

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Bibliografske podrobnosti
Main Authors: Stavrou, Spyridon, Nitta, Takayuki, Kotla, Swathi, Ha, Dat, Nagashima, Kunio, Rein, Alan R., Fan, Hung, Ross, Susan R.
Format: Artigo
Jezik:Inglês
Izdano: National Academy of Sciences 2013
Teme:
Biological Sciences
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC3670389/
https://ncbi.nlm.nih.gov/pubmed/23671100
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1217399110
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