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The JAK-STAT pathway and hematopoietic stem cells from the JAK2 V617F perspective

Janus kinases (JAKs) are non-receptor tyrosine kinases essential for activation of signaling mediated by cytokine receptors that lack catalytic activity, including receptors for erythropoietin, thrombopoietin, most interleukins and interferon. Upon hormone binding, JAKs phosphorylate tyrosine residu...

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Bibliografische gegevens
Hoofdauteurs: Staerk, Judith, Constantinescu, Stefan N.
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: Landes Bioscience 2012
Onderwerpen:
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3670242/
https://ncbi.nlm.nih.gov/pubmed/24058768
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4161/jkst.22071
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