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The JAK-STAT pathway and hematopoietic stem cells from the JAK2 V617F perspective
Janus kinases (JAKs) are non-receptor tyrosine kinases essential for activation of signaling mediated by cytokine receptors that lack catalytic activity, including receptors for erythropoietin, thrombopoietin, most interleukins and interferon. Upon hormone binding, JAKs phosphorylate tyrosine residu...
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| Autores principales: | , |
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| Formato: | Artigo |
| Lenguaje: | Inglês |
| Publicado: |
Landes Bioscience
2012
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| Materias: | |
| Acceso en línea: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3670242/ https://ncbi.nlm.nih.gov/pubmed/24058768 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4161/jkst.22071 |
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