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The interaction of octopamine and neuropeptides to slow aversive responses in C. elegans mimics the modulation of chronic pain in mammals

Octopamine (OA) appears to function as the invertebrate counterpart of norepinephrine (NE) in the modulation of a number of key behaviors. In C. elegans, OA signaling is complex, mediated by at least three distinct α-adrenergic-like receptors and appears to activate more global peptidergic signaling...

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Détails bibliographiques
Auteurs principaux: Mills, Holly, Hapiak, Vera, Harris, Gareth, Summers, Phillip, Komuniecki, Richard
Format: Artigo
Langue:Inglês
Publié: Landes Bioscience 2012
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC3670219/
https://ncbi.nlm.nih.gov/pubmed/24058849
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4161/worm.20467
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