A membrane penetrating peptide aptamer inhibits STAT3 function and suppresses the growth of STAT3 addicted tumor cells

Cancer cells are characterized by the aberrant activation of signaling pathways governing proliferation, survival, angiogenesis, migration and immune evasion. These processes are partially regulated by the transcription factor STAT3. This factor is inappropriately activated in diverse tumor types. S...

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Bibliographic Details
Main Authors: Borghouts, Corina, Delis, Natalia, Brill, Boris, Weiss, Astrid, Mack, Laura, Lucks, Peter, Groner, Bernd
Format: Artigo
Language:Inglês
Published: Landes Bioscience 2012
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Research Paper
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3670134/
https://ncbi.nlm.nih.gov/pubmed/24058750
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4161/jkst.18947
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