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Post-translational Acetylation of α Tubulin Constrains Protofilament Number in Native Microtubules

BACKGROUND: Microtubules are built from linear polymers of α-β tubulin dimers (protofilaments) that form a tubular quinary structure. Microtubules assembled from purified tubulin in vitro contain between ten and sixteen protofilaments, however such structural polymorphisms are not found in cells. Th...

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Main Authors: Cueva, Juan G., Hsin, Jen, Huang, K. C., Goodman, Miriam B.
Formato: Artigo
Idioma:Inglês
Publicado: 2012
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC3670109/
https://ncbi.nlm.nih.gov/pubmed/22658592
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cub.2012.05.012
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