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Use of Gel Zymography to Examine Matrix Metalloproteinase (Gelatinase) Expression in Brain Tissue or in Primary Glial Cultures

Glia synthesize, package, and secrete several species of matrix proteases, including the gelatinases (pro-)MMP-2 and (pro-)MMP-9. In appropriate settings (e.g., experimental ischemia), these MMPs can be assayed from cerebral tissues or from astrocytes and microglia in culture by enzymatic substrate-...

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Autores principales: Frankowski, Harald, Gu, Yu-Huan, Heo, Ji Hoe, Milner, Richard, del Zoppo, Gregory J.
Formato: Artigo
Lenguaje:Inglês
Publicado: 2012
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC3670093/
https://ncbi.nlm.nih.gov/pubmed/22144310
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/978-1-61779-452-0_15
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