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Adenovirus E1B proteins are required for accumulation of late viral mRNA and for effects on cellular mRNA translation and transport.

Late in adenovirus infection, large amounts of viral mRNA accumulate while cell mRNA transport and translation decrease. Viruses deleted in the E1B region of type 5 adenovirus do not produce the same outcome: (i) viral mRNA synthesis by the mutants is normal, delivery to the cytoplasm is 50 to 75% o...

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Bibliografiske detaljer
Udgivet i:Mol Cell Biol
Principais autores: Babiss, L E, Ginsberg, H S, Darnell, J E
Format: Artigo
Sprog:Inglês
Udgivet: Taylor & Francis 1985
Fag:
Online adgang:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC366989/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/2942759/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/mcb.5.10.2552-2558.1985
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