The interaction of celecoxib with MDR transporters enhances the activity of mitomycin C in a bladder cancer cell line

BACKGROUND: An in vitro model was developed to understand if celecoxib could synergize with Mitomycin C (MMC), commonly used for the prevention of non-muscle invasive bladder cancer recurrence, and eventually elucidate if the mechanism of interaction involves multi drug resistance (MDR) transporters...

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Autores principales: Pagliarulo, Vincenzo, Ancona, Patrizia, Niso, Mauro, Colabufo, Nicola Antonio, Contino, Marialessandra, Cormio, Luigi, Azzariti, Amalia, Pagliarulo, Arcangelo
Formato: Artigo
Lenguaje:Inglês
Publicado: BioMed Central 2013
Materias:
Research
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC3669624/
https://ncbi.nlm.nih.gov/pubmed/23705854
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1476-4598-12-47
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