Increased Beta2-Adrenoceptors in Doxorubicin-Induced Cardiomyopathy in Rat

BACKGROUND: The toxicity of doxorubicin, leading to an irreversible heart failure, limits its use as chemotherapeutic agent. The beneficial effects of early administration of β-blocker were reported in patients with heart failure due to doxorubicin, suggesting an important role of β-adrenoceptors (β...

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Main Authors: Merlet, Nolwenn, Piriou, Nicolas, Rozec, Bertrand, Grabherr, Amandine, Lauzier, Benjamin, Trochu, Jean-Noël, Gauthier, Chantal
Format: Artigo
Sprog:Inglês
Udgivet: Public Library of Science 2013
Fag:
Research Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3669386/
https://ncbi.nlm.nih.gov/pubmed/23741376
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0064711
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