Cadmium-Induced Apoptosis in Primary Rat Cerebral Cortical Neurons Culture Is Mediated by a Calcium Signaling Pathway

Cadmium (Cd) is an extremely toxic metal, capable of severely damaging several organs, including the brain. Studies have shown that Cd disrupts intracellular free calcium ([Ca(2+)](i)) homeostasis, leading to apoptosis in a variety of cells including primary murine neurons. Calcium is a ubiquitous i...

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Detalhes bibliográficos
Main Authors: Yuan, Yan, Jiang, Chen-yang, Xu, Hui, Sun, Ya, Hu, Fei-fei, Bian, Jian-chun, Liu, Xue-zhong, Gu, Jian-hong, Liu, Zong-ping
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2013
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Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3669330/
https://ncbi.nlm.nih.gov/pubmed/23741317
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0064330
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