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RNA-mediated gene duplication: the rat preproinsulin I gene is a functional retroposon.

Rats and mice have two, equally expressed, nonallelic genes encoding preproinsulin (genes I and II). Cytological hybridization with metaphase chromosomes indicated that both genes reside on rat chromosome I but are approximately 100,000 kilobases apart. In mice the two genes reside on two different...

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Publicat a:Mol Cell Biol
Autors principals: Soares, M B, Schon, E, Henderson, A, Karathanasis, S K, Cate, R, Zeitlin, S, Chirgwin, J, Efstratiadis, A
Format: Artigo
Idioma:Inglês
Publicat: Taylor & Francis 1985
Matèries:
Accés en línia:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC366927/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/2427930/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/mcb.5.8.2090-2103.1985
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