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Age-Associated Metabolic and Morphologic Changes in Mitochondria of Individual Mouse and Hamster Oocytes

BACKGROUND: In human oocytes, as in other mammalian ova, there is a significant variation in the pregnancy potential, with approximately 20% of oocyte-sperm meetings resulting in pregnancies. This frequency of successful fertilization decreases as the oocytes age. This low proportion of fruitful cou...

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Main Authors: Simsek-Duran, Fatma, Li, Fang, Ford, Wentia, Swanson, R. James, Jones, Howard W., Castora, Frank J.
פורמט: Artigo
שפה:Inglês
יצא לאור: Public Library of Science 2013
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גישה מקוונת:https://ncbi.nlm.nih.gov/pmc/articles/PMC3669215/
https://ncbi.nlm.nih.gov/pubmed/23741435
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0064955
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