Robust Automated Detection of Microstructural White Matter Degeneration in Alzheimer’s Disease Using Machine Learning Classification of Multicenter DTI Data

Diffusion tensor imaging (DTI) based assessment of white matter fiber tract integrity can support the diagnosis of Alzheimer’s disease (AD). The use of DTI as a biomarker, however, depends on its applicability in a multicenter setting accounting for effects of different MRI scanners. We applied mult...

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Hauptverfasser: Dyrba, Martin, Ewers, Michael, Wegrzyn, Martin, Kilimann, Ingo, Plant, Claudia, Oswald, Annahita, Meindl, Thomas, Pievani, Michela, Bokde, Arun L. W., Fellgiebel, Andreas, Filippi, Massimo, Hampel, Harald, Klöppel, Stefan, Hauenstein, Karlheinz, Kirste, Thomas, Teipel, Stefan J.
Format: Artigo
Sprache:Inglês
Veröffentlicht: Public Library of Science 2013
Schlagworte:
Research Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3669206/
https://ncbi.nlm.nih.gov/pubmed/23741425
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0064925
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