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Improving health from the inside: Use of engineered intestinal microorganisms as in situ cytokine delivery system

The anti-inflammatory cytokine interleukin-10 and its viral homologs were chosen as model proteins for the development of drug delivery systems based on probiotic carriers like E. coli Nissle 1917, E. coli G3/10, and Saccharomyces boulardii. Exterior cytokine secretion was achieved by a modified E....

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Detalhes bibliográficos
Main Authors: Pöhlmann, Christoph, Thomas, Mandy, Förster, Sarah, Brandt, Manuela, Hartmann, Maike, Bleich, André, Gunzer, Florian
Formato: Artigo
Idioma:Inglês
Publicado em: Landes Bioscience 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3669160/
https://ncbi.nlm.nih.gov/pubmed/23111320
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4161/bioe.22646
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