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Genetic background (DDD/Sgn versus C57BL/6J) strongly influences postnatal growth of male mice carrying the A(y) allele at the agouti locus: identification of quantitative trait loci associated with diabetes and body weight loss

BACKGROUND: Mice carrying the A(y) allele at the agouti locus become obese and are heavier than their non-A(y) littermates. However, this does not hold true for the genetic background of the DDD mouse strain. At 22 weeks of age, DDD.Cg-A(y) females are heavier than DDD females, whereas DDD.Cg-A(y) m...

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Detalhes bibliográficos
Main Authors: Suto, Jun-ichi, Satou, Kunio
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3669036/
https://ncbi.nlm.nih.gov/pubmed/23641944
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2156-14-35
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