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Insights on altered mitochondrial function and dynamics in the pathogenesis of neurodegeneration

In neurons, mitochondria are enriched to provide energy and calcium buffering required for synaptic transmission. Additionally, mitochondria localize to the synapse, where they are critical for the mobilization of reserve pool vesicles and for neurotransmitter release. Previously, functional defects...

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Detalhes bibliográficos
Autor principal: McInnes, Joseph
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3669018/
https://ncbi.nlm.nih.gov/pubmed/23711354
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/2047-9158-2-12
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