Aspirin Minimized the Pro-Metastasis Effect of Sorafenib and Improved Survival by Up-Regulating HTATIP2 in Hepatocellular Carcinoma

BACKGROUND & AIMS: We previously demonstrated the pro-metastasis effect of sorafenib in hepatocellular carcinoma (HCC), which is mediated by down-regulation of tumor suppressor HTATIP2. The aim of the present study was to determine whether aspirin minimizes this effect and improves survival. MET...

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Bibliographic Details
Main Authors: Lu, Lu, Sun, Hui-Chuan, Zhang, Wei, Chai, Zong-Tao, Zhu, Xiao-Dong, Kong, Ling-Qun, Wang, Wen-Quan, Zhang, Ke-Zhi, Zhang, Yuan-Yuan, Zhang, Qiang-Bo, Ao, Jian-Yang, Li, Jia-Qi, Wang, Lu, Wu, Wei-Zhong, Tang, Zhao-You
Format: Artigo
Language:Inglês
Published: Public Library of Science 2013
Subjects:
Research Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3669011/
https://ncbi.nlm.nih.gov/pubmed/23741443
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0065023
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