Valproic Acid and Topiramate Induced Hyperammonemic Encephalopathy in a Patient With Normal Serum Carnitine

A 17-year-old female developed hyperammonemic encephalopathy 2 weeks after valproic acid (VPA), 500 mg twice a day, was added to her regimen of topiramate (TPM), 200 mg twice a day. She presented to the emergency department (ED) with altered mental status, hypotension, bradycardia, and lethargy. Lab...

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Bibliographic Details
Main Authors: Blackford, Martha G., Do, Stephanie T., Enlow, Thomas C., Reed, Michael D.
Format: Artigo
Language:Inglês
Published: Pediatric Pharmacy Advocacy Group 2013
Subjects:
Case Reports
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3668941/
https://ncbi.nlm.nih.gov/pubmed/23798907
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.5863/1551-6776-18.2.128
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