HPV-related methylation signature predicts survival in oropharyngeal squamous cell carcinomas

High-risk types of human papilloma virus (HPV) are increasingly associated with oropharyngeal squamous cell carcinoma (OPSCC). Strikingly, patients with HPV-positive OPSCC are highly curable with ionizing radiation and have better survival compared with HPV-negative patients, but the underlying mole...

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Hlavní autoři: Kostareli, Efterpi, Holzinger, Dana, Bogatyrova, Olga, Hielscher, Thomas, Wichmann, Gunnar, Keck, Michaela, Lahrmann, Bernd, Grabe, Niels, Flechtenmacher, Christa, Schmidt, Christopher R., Seiwert, Tanguy, Dyckhoff, Gerhard, Dietz, Andreas, Höfler, Daniela, Pawlita, Michael, Benner, Axel, Bosch, Franz X., Plinkert, Peter, Plass, Christoph, Weichenhan, Dieter, Hess, Jochen
Médium: Artigo
Jazyk:Inglês
Vydáno: American Society for Clinical Investigation 2013
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Research Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3668826/
https://ncbi.nlm.nih.gov/pubmed/23635773
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI67010
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