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Integrin-Linked Kinase Regulates PTEN Activity to Promote Tumorigenesis in Neuroblastoma Cells
BACKGROUND: The phosphatidylinositol 3-kinase (PI3K), a critical intracellular pathway, is negatively regulated by phosphatase and tensin homologue (PTEN). Integrin-linked kinase (ILK) induces phosphorylation of Akt leading to an increase in cell survival. However, a potential interaction between IL...
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| Main Authors: | , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2011
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3668783/ https://ncbi.nlm.nih.gov/pubmed/21719054 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.surg.2011.05.007 |
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