Acidic Domain in Dentin Phosphophoryn Facilitates Cellular Uptake: IMPLICATIONS IN TARGETED PROTEIN DELIVERY

Dentin phosphophoryn is nature's most acidic protein found predominantly in the dentin extracellular matrix. Its unique amino acid composition containing Asp-Ser (DS)-rich repeats makes it highly anionic. It has a low isoelectric point (pI 1.1) and, therefore, tends to be negatively charged at...

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Autori principali: Ravindran, Sriram, Snee, Preston T., Ramachandran, Amsaveni, George, Anne
Natura: Artigo
Lingua:Inglês
Pubblicazione: American Society for Biochemistry and Molecular Biology 2013
Soggetti:
Cell Biology
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3668765/
https://ncbi.nlm.nih.gov/pubmed/23589294
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M113.450585
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